Combination Therapy for Merkel Cell Carcinoma
نویسندگان
چکیده
منابع مشابه
Systemic Therapy for Merkel Cell Carcinoma: What’s on the Horizon?
Merkel cell carcinoma is an aggressive neuroendocrine skin cancer that usually affects elderly patients. Despite being uncommon, incidence has been steadily increasing over the last two decades, likely due to increased awareness, better diagnostic methods and aging of the population. It is currently one of the most lethal cutaneous malignancies, with a five-year overall survival of approximatel...
متن کاملDigital Merkel cell carcinoma.
Merkel cell carcinoma (MCC) is a rare and biologically aggressive neuroendocrine tumour of the skin. Recent analysis of a surveillance, epidemiology and end results program has shown a statistically significant increase of 8% per year in the age-adjusted rates for MCC of the skin over the past 15 years. MCC commonly presents as a painless, rapidly growing, single red or purple cutaneous nodule....
متن کاملMerkel cell carcinoma
BACKGROUND Merkel cell carcinoma (MCC) is an unusual primary neuroendocrine carcinoma of the skin. MCC is a fatal disease, and patients have a poor chance of survival. Moreover, MCC lacks distinguishing clinical features, and thus by the time the diagnosis is made, the tumour usually have metastasized. MCC mainly affects sun-exposed areas of elderly persons. Half of the tumours are located in t...
متن کاملMerkel cell carcinoma.
Merkel cell carcinoma is a rare, highly aggressive neuroendocrine cutaneous neoplasm with a variable clinical presentation. Histologically, it is a predominantly dermal-based lesion composed of monotonous small round cells with scanty cytoplasm, often difficult to differentiate from small round cell tumors, metastatic small cell carcinoma, blastic hematologic malignancies, and melanoma. The mal...
متن کاملMerkel cell carcinoma.
IN 1875, FRIEDRICH Sigmund Merkel (1845-1919) described a unique epidermal nondendritic, nonkeratinocyte cell, which he called a tactile cell (Tastzelle). This cell, now bearing his name, was thought to be a primary touch receptor. Merkel cells are now generally believed to be primary neural cells, found as single cells within the basal layer of the epidermis or grouped together as a component ...
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ژورنال
عنوان ژورنال: Journal of Biomedical Sciences
سال: 2016
ISSN: 2254-609X
DOI: 10.4172/2254-609x.100041